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Overview

Hypopituitarism is a rare pituitary gland disorder in which the pituitary gland is unable to produce its hormones in sufficient quantities. The pituitary gland is a small, pea-sized gland situated below the brain, just behind the bridge of the nose. It is responsible for secreting hormones that control the functioning of several other hormone glands in the body like the thyroid gland, the adrenal glands, the ovaries and the testicles. In hypopituitarism, the reduced amount of pituitary hormones disturbs the body's normal functions, such as growth, blood pressure and reproduction.

Symptoms

The symptoms of hypopituitarism include: Increased sensitivity towards cold Poor appetite Weakness and fatigue Anemia Swelling in the face Disturbed menstrual cycles Pubic hair loss Infertility Weight loss Low sexual appetite Decreased facial or body hair in men Retarded growth in childrenDFDAFF


Causes

The causes of hypopituitarism include: Injury to the head Stroke Brain infections like meningitis Radiation treatment Autoimmune inflammation Excessive loss of blood during childbirth Genetic mutations Tuberculosis Inflammatory diseases like sarcoidosis Presence of tumours in the brain or pituitary gland Brain surgery


Diagnosis

In order to diagnose hypopituitarism, the doctor conducts the following tests to check the levels of various hormones like Adrenocorticotropic Hormone, Growth Hormone and Thyroid Stimulating Hormone etc. in the body. Blood tests MRI scan Vision tests Stimulation testing


Treatments

Treatment for hypopituitarism includes treating the underlying cause to completely or partially restore the pituitary function. The doctor opts for certain drugs which act as a replacement for the pituitary hormones that the body would have manufactured in the absence of a pituitary problem. Hormone replacement drugs include: Corticosteroids These are oral drugs that act as a replacement for the adrenal hormones. Levothyroxine This medicine acts as a replacement for thyroid hormones. Sex hormones Sex hormones used for men are testosterone while estrogen or a combination of estrogen and progesterone are used for women to treat hypopituitarism. Growth hormone The growth hormone, when injected into the skin, promotes growth in children.


Prevention

The risk of developing hypopituitarism due to child birth can be decreased by taking proper obstetric care. Regular monitoring and health check-ups especially during periods of stress, infections may help in preventing the disease.


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